IL-17, synoviolin and rheumatoid arthritis chronicity

Role of Interleukin 17 in Arthritis Chronicity through Survival of Synoviocytes via Regulation of Synoviolin Expression

BACKGROUND The use of TNF inhibitors has been a major progress in the treatment of chronic inflammation. However, not all patients respond. In addition, response will be often lost when treatment is stopped. These clinical aspects indicate that other cytokines might be involved and we focus here on the role of IL-17. In addition, the chronic nature of joint inflammation may contribute to reduce...

Role of Interleukin 17 in arthritis chronicity through survival of synoviocytes via regulation of synoviolin

Background: The use of TNF inhibitors has been a major progress in the treatment of chronic inflammation. However, not all patients respond. In addition, response will be often lost when treatment is stopped. These clinical aspects indicate that other cytokines might be involved and we focus here on the role of IL-17. In addition, the chronic nature of joint inflammation may contribute to reduc...

reviews Title : IL 17 A and IL 17 F gene polymorphisms in patients with rheumatoid arthritis

serum levels of il-17, il-4, and infî³ in serbian patients with early rheumatoid arthritis

background: rheumatoid arthritis (ra) is a chronic, systemic, inflammatory disease with autoimmune etiology, characterized by synovial inflammation and destruction of joint cartilage and bone. there are controversial data about the profile of interleukin-17 (il-17a), interleukin-4 (il-4), and interferon-gamma (infî³), indicating in some studies the key role of il-17, while in others the th1 cyt...

Rheumatoid Arthritis IL-17 Induces Monocyte Migration in